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STEMCELL Technologies Inc human cd14 + peripheral blood-derived monocytes
A) Higher levels of resistin significantly positively correlated to delta values in KOOS Sports/Rec scores at 24 months. Higher levels of TIMP1 and CCL2 significantly correlated inversely to the percentage change and/or delta in KOOS Sports/Rec scores at 24 months relative to baseline. B) Higher levels of HGF and VEGFA in synovial fluid significantly correlated inversely to delta values and/or percentage change in KOOS Pain scores at 12 months relative to baseline. C) Higher levels of sCD14 and CCL2 significantly correlate inversely to the percentage change and/or delta in KOOS Symptom and Sports/Rec scores at 3 months relative to baseline. Delta and percent change in KOOS values were made relative to baseline and calculated such that positive values represent improvement. N=8-9 patients. Spearman’s correlation. Sports/Rec: function in sport and recreation; MO: month; KOOS: knee injury and osteoarthritis outcome score; TIMP1: tissue inhibitor of metalloproteinases 1; CCL2: chemokine C-C motif ligand 2; HGF: hepatocyte growth factor; sCD14: soluble <t>CD14;</t> VEGFA: vascular endothelial growth factor A.
Human Cd14 + Peripheral Blood Derived Monocytes, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/human+cd14+++peripheral+blood-derived+monocytes/easysep+human+t+cell+isolation+kit/bio_rxiv__2025__07__17__665028-54-4-10
Average 90 stars, based on 1 article reviews
human cd14 + peripheral blood-derived monocytes - by Bioz Stars, 2026-10
90/100 stars

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1) Product Images from "Responders vs. non-responders to mesenchymal stromal cells in knee osteoarthritis patients: mechanistic correlates of donor cell attributes and patient features"

Article Title: Responders vs. non-responders to mesenchymal stromal cells in knee osteoarthritis patients: mechanistic correlates of donor cell attributes and patient features

Journal: bioRxiv

doi: 10.1101/2025.07.17.665028

A) Higher levels of resistin significantly positively correlated to delta values in KOOS Sports/Rec scores at 24 months. Higher levels of TIMP1 and CCL2 significantly correlated inversely to the percentage change and/or delta in KOOS Sports/Rec scores at 24 months relative to baseline. B) Higher levels of HGF and VEGFA in synovial fluid significantly correlated inversely to delta values and/or percentage change in KOOS Pain scores at 12 months relative to baseline. C) Higher levels of sCD14 and CCL2 significantly correlate inversely to the percentage change and/or delta in KOOS Symptom and Sports/Rec scores at 3 months relative to baseline. Delta and percent change in KOOS values were made relative to baseline and calculated such that positive values represent improvement. N=8-9 patients. Spearman’s correlation. Sports/Rec: function in sport and recreation; MO: month; KOOS: knee injury and osteoarthritis outcome score; TIMP1: tissue inhibitor of metalloproteinases 1; CCL2: chemokine C-C motif ligand 2; HGF: hepatocyte growth factor; sCD14: soluble CD14; VEGFA: vascular endothelial growth factor A.
Figure Legend Snippet: A) Higher levels of resistin significantly positively correlated to delta values in KOOS Sports/Rec scores at 24 months. Higher levels of TIMP1 and CCL2 significantly correlated inversely to the percentage change and/or delta in KOOS Sports/Rec scores at 24 months relative to baseline. B) Higher levels of HGF and VEGFA in synovial fluid significantly correlated inversely to delta values and/or percentage change in KOOS Pain scores at 12 months relative to baseline. C) Higher levels of sCD14 and CCL2 significantly correlate inversely to the percentage change and/or delta in KOOS Symptom and Sports/Rec scores at 3 months relative to baseline. Delta and percent change in KOOS values were made relative to baseline and calculated such that positive values represent improvement. N=8-9 patients. Spearman’s correlation. Sports/Rec: function in sport and recreation; MO: month; KOOS: knee injury and osteoarthritis outcome score; TIMP1: tissue inhibitor of metalloproteinases 1; CCL2: chemokine C-C motif ligand 2; HGF: hepatocyte growth factor; sCD14: soluble CD14; VEGFA: vascular endothelial growth factor A.

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Article Title: Responders vs. non-responders to mesenchymal stromal cells in knee osteoarthritis patients: mechanistic correlates of donor cell attributes and patient features
Article Snippet: Indirect co-culture of unmatched human CD14 + peripheral blood-derived monocytes (STEMCELL Technologies, Vancouver, Canada) with biobanked MSC(M) was performed as previously described [ ].



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A) Higher levels of resistin significantly positively correlated to delta values in KOOS Sports/Rec scores at 24 months. Higher levels of TIMP1 and CCL2 significantly correlated inversely to the percentage change and/or delta in KOOS Sports/Rec scores at 24 months relative to baseline. B) Higher levels of HGF and VEGFA in synovial fluid significantly correlated inversely to delta values and/or percentage change in KOOS Pain scores at 12 months relative to baseline. C) Higher levels of sCD14 and CCL2 significantly correlate inversely to the percentage change and/or delta in KOOS Symptom and Sports/Rec scores at 3 months relative to baseline. Delta and percent change in KOOS values were made relative to baseline and calculated such that positive values represent improvement. N=8-9 patients. Spearman’s correlation. Sports/Rec: function in sport and recreation; MO: month; KOOS: knee injury and osteoarthritis outcome score; TIMP1: tissue inhibitor of metalloproteinases 1; CCL2: chemokine C-C motif ligand 2; HGF: hepatocyte growth factor; sCD14: soluble <t>CD14;</t> VEGFA: vascular endothelial growth factor A.
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A) Higher levels of resistin significantly positively correlated to delta values in KOOS Sports/Rec scores at 24 months. Higher levels of TIMP1 and CCL2 significantly correlated inversely to the percentage change and/or delta in KOOS Sports/Rec scores at 24 months relative to baseline. B) Higher levels of HGF and VEGFA in synovial fluid significantly correlated inversely to delta values and/or percentage change in KOOS Pain scores at 12 months relative to baseline. C) Higher levels of sCD14 and CCL2 significantly correlate inversely to the percentage change and/or delta in KOOS Symptom and Sports/Rec scores at 3 months relative to baseline. Delta and percent change in KOOS values were made relative to baseline and calculated such that positive values represent improvement. N=8-9 patients. Spearman’s correlation. Sports/Rec: function in sport and recreation; MO: month; KOOS: knee injury and osteoarthritis outcome score; TIMP1: tissue inhibitor of metalloproteinases 1; CCL2: chemokine C-C motif ligand 2; HGF: hepatocyte growth factor; sCD14: soluble <t>CD14;</t> VEGFA: vascular endothelial growth factor A.
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A) Higher levels of resistin significantly positively correlated to delta values in KOOS Sports/Rec scores at 24 months. Higher levels of TIMP1 and CCL2 significantly correlated inversely to the percentage change and/or delta in KOOS Sports/Rec scores at 24 months relative to baseline. B) Higher levels of HGF and VEGFA in synovial fluid significantly correlated inversely to delta values and/or percentage change in KOOS Pain scores at 12 months relative to baseline. C) Higher levels of sCD14 and CCL2 significantly correlate inversely to the percentage change and/or delta in KOOS Symptom and Sports/Rec scores at 3 months relative to baseline. Delta and percent change in KOOS values were made relative to baseline and calculated such that positive values represent improvement. N=8-9 patients. Spearman’s correlation. Sports/Rec: function in sport and recreation; MO: month; KOOS: knee injury and osteoarthritis outcome score; TIMP1: tissue inhibitor of metalloproteinases 1; CCL2: chemokine C-C motif ligand 2; HGF: hepatocyte growth factor; sCD14: soluble <t>CD14;</t> VEGFA: vascular endothelial growth factor A.
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A) Higher levels of resistin significantly positively correlated to delta values in KOOS Sports/Rec scores at 24 months. Higher levels of TIMP1 and CCL2 significantly correlated inversely to the percentage change and/or delta in KOOS Sports/Rec scores at 24 months relative to baseline. B) Higher levels of HGF and VEGFA in synovial fluid significantly correlated inversely to delta values and/or percentage change in KOOS Pain scores at 12 months relative to baseline. C) Higher levels of sCD14 and CCL2 significantly correlate inversely to the percentage change and/or delta in KOOS Symptom and Sports/Rec scores at 3 months relative to baseline. Delta and percent change in KOOS values were made relative to baseline and calculated such that positive values represent improvement. N=8-9 patients. Spearman’s correlation. Sports/Rec: function in sport and recreation; MO: month; KOOS: knee injury and osteoarthritis outcome score; TIMP1: tissue inhibitor of metalloproteinases 1; CCL2: chemokine C-C motif ligand 2; HGF: hepatocyte growth factor; sCD14: soluble <t>CD14;</t> VEGFA: vascular endothelial growth factor A.
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A) Higher levels of resistin significantly positively correlated to delta values in KOOS Sports/Rec scores at 24 months. Higher levels of TIMP1 and CCL2 significantly correlated inversely to the percentage change and/or delta in KOOS Sports/Rec scores at 24 months relative to baseline. B) Higher levels of HGF and VEGFA in synovial fluid significantly correlated inversely to delta values and/or percentage change in KOOS Pain scores at 12 months relative to baseline. C) Higher levels of sCD14 and CCL2 significantly correlate inversely to the percentage change and/or delta in KOOS Symptom and Sports/Rec scores at 3 months relative to baseline. Delta and percent change in KOOS values were made relative to baseline and calculated such that positive values represent improvement. N=8-9 patients. Spearman’s correlation. Sports/Rec: function in sport and recreation; MO: month; KOOS: knee injury and osteoarthritis outcome score; TIMP1: tissue inhibitor of metalloproteinases 1; CCL2: chemokine C-C motif ligand 2; HGF: hepatocyte growth factor; sCD14: soluble CD14; VEGFA: vascular endothelial growth factor A.

Journal: bioRxiv

Article Title: Responders vs. non-responders to mesenchymal stromal cells in knee osteoarthritis patients: mechanistic correlates of donor cell attributes and patient features

doi: 10.1101/2025.07.17.665028

Figure Lengend Snippet: A) Higher levels of resistin significantly positively correlated to delta values in KOOS Sports/Rec scores at 24 months. Higher levels of TIMP1 and CCL2 significantly correlated inversely to the percentage change and/or delta in KOOS Sports/Rec scores at 24 months relative to baseline. B) Higher levels of HGF and VEGFA in synovial fluid significantly correlated inversely to delta values and/or percentage change in KOOS Pain scores at 12 months relative to baseline. C) Higher levels of sCD14 and CCL2 significantly correlate inversely to the percentage change and/or delta in KOOS Symptom and Sports/Rec scores at 3 months relative to baseline. Delta and percent change in KOOS values were made relative to baseline and calculated such that positive values represent improvement. N=8-9 patients. Spearman’s correlation. Sports/Rec: function in sport and recreation; MO: month; KOOS: knee injury and osteoarthritis outcome score; TIMP1: tissue inhibitor of metalloproteinases 1; CCL2: chemokine C-C motif ligand 2; HGF: hepatocyte growth factor; sCD14: soluble CD14; VEGFA: vascular endothelial growth factor A.

Article Snippet: Indirect co-culture of unmatched human CD14 + peripheral blood-derived monocytes (STEMCELL Technologies, Vancouver, Canada) with biobanked MSC(M) was performed as previously described [ ].

Techniques: